A Navarra regional government statement said the two men were gored in the leg and another five people were taken to Pamplona hospitals for minor injuries sustained in the 8 a.m. dash Thursday.
The gorings were caused by a lone bull that raced ahead of the pack, raising panic among the hundreds of screaming runners along the 930-yard (850-meter) course from a holding pen to Pamplona's bull ring.
The morning runs are the highlight of the nine-day street-partying festival, which was immortalized in Ernest Hemingway's 1926 novel "The Sun Also Rises" and attracts thousands of foreign tourists.
Dozens of people are injured each year in the runs, most of them in falls.
Fifteen people have died from gorings since record-keeping began in 1924.
Four Spaniards and one American have been gored so far in this year's festival but only one, a Spaniard, was said to be in serious condition.
The six bulls used in each run are invariably killed in afternoon bullfights in the ring.
(AP)
